Discontinuous polyostotic fibrous dysplasia with multiple systemic disorders and unique genetic mutations: A case report

Polyostotic fibrous dysplasia; a case report.

Fibrous dysplasia is a condition leading to abnormal differentiation of osteoblasts which leads to replacement of normal bone with fibrous stroma [1-3]. It may involve single bone (monostotic) or multiple bones (polyostotic). It may affect any bone however; skull and ribs are the commonest [2,4-6]. It is usually asymptomatic and is an incidental finding. It may become symptomatic when complicat...

A case of craniofacial polyostotic fibrous dysplasia.

We present the case of a patient with craniofacial polyostotic fibrous dysplasia. Polyostotic fibrous dysplasia is relatively rare and usually presents in late childhood/early adulthood. It is occasionally associated with endocrine disorders such as McCune-Albright syndrome. The benign pathology of this bone tumor belies its implications in the region of the skull base. Craniofacial polyostotic...

Polyostotic fibrous dysplasia.

An 18-year-old man was referred to the authors' institution's thoracic cancer specialists for further consultation after abnormal findings were seen on chest radiograph.

Polyostotic fibrous displasia: a case report.

A 37-year-old woman with a fibrous polyostotic dysplasia (FPD) of the left femur, tibia and foot was diagnosed at 11 years of age. At the onset she presented mechanical pain of the left hip and later a stress fracture of the femur for which she was treated with surgery, pamidronate and zolendronate. Pathology confirmed the diagnosis. Phosphocalcic metabolism was normal. X-rays (Fig. 1) showeda ...

[Polyostotic fibrous dysplasia: Albright's syndrome].